Excessive fat accumulation in fat cells leads to chronic low-grade inflammation, with chronically elevated levels of damaging compounds known as proinflammatory cytokines, which contribute to the development of metabolic diseases.
Research shows that exercise can reduce the risk of obesity-related complications. In a study presented at the European Congress on Obesity, researchers wanted to investigate whether combining aerobic exercise with weight loss medication could reduce chronic low-grade inflammation in obese people. Study volunteers had two sessions per week of mostly vigorous aerobic exercise on spinning bikes. They were also encouraged to reach a minimum of 150 minutes per week of aerobic activity. Researchers found that exercise was the most effective strategy to reduce chronic low-grade obesity-related inflammation.